Tumour-necrosis factor from the rabbit. II. Production by monocytes
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چکیده
منابع مشابه
Dietary beta-carotene supplementation modulates the production of tumour necrosis factor-alpha by human monocytes.
Epidemiological studies have shown a strong inverse association between intake of the antioxidant carotenoid, 8-carotene, and the incidence of cancer [l]. The immune system plays a major role in cancer prevention and it has been suggested that 8-carotene might prevent carcinogenesis by enhancing immune cell activity [2]. Tumour necrosis factor-a (TNF), an immunostimulatory cytokine secreted by ...
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Preoperative oral treatment with lactulose is used to prevent complications after surgery in patients with obstructive jaundice. The effect is perhaps the result of an inactivation of gut derived endotoxins but the exact mechanism of action is, however, unknown. Tumour necrosis factor is an important mediator of endotoxin toxicity. The cytokine tumour necrosis factor is mainly produced by monon...
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The purpose of this study was to evaluate the effect of theophylline on tumour necrosis factor-alpha (TNF-alpha) release by human blood monocytes (BMo), and rat BMo and alveolar macrophages (AM). BMo and AM were incubated in the absence or presence of theophylline, and the cell-free supernatants were harvested and tested for TNF-alpha activity by bioassay. Theophylline dose-dependently reduced ...
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We studied the production of tumor necrosis factor alpha (TNF-alpha) by peripheral blood monocytes taken from patients with pulmonary tuberculosis and from healthy controls. It was found that the monocytes from patients with newly diagnosed tuberculosis released significantly greater amounts of TNF-alpha in vitro in response to lipopolysaccharide than did those from healthy controls (P less tha...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1978
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1978.203